Tsuyoshi Matsumoto

Affiliation: Department of Chemistry, Graduate School of Science, Nagoya University,

Address: Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan

Phone: +81-52-789-5905

FAX:   +81-52-789-2943

E-mail: tmatsu@chem.nagoya-u.ac.jp

Date of Birth: September 4, 1966.


Education and Carrier:

1990        B.Sc., Chemistry, The University of Tokyo

1992        M.Sc., Chemistry, The University of Tokyo

1995        Ph.D, Chemistry, The University of Tokyo

1992–1995   Research Fellow of JSPS (DC1)

1995–1998   Toray Industries, Inc. (Basic Research Lab., Medicinal Chemistry)

1998–present Assistant Professor, Nagoya University


Research Interests:

1) Activation of Small Molecules Modeling the Metalloenzymes (Hydrogenase, Acetyl CoA Synthase, Methyl CoM Reductase, CO-dehydrogenase).

2) Chemistry of Main Group Elements (Group 14, 16).


Recent Publications:

1.      “A Dinuclear Nickel Complex Modeling the Nid(II)-Nip(I) State for the Active Site of Acetyl CoA Synthase”, Matsumoto, T.; Ito, M.; Kotera, M.; Tatsumi, K. Dalton Trans. 2010, In press (invited paper).

2.      Host plant genome overcomes the lack of bacterial gene for symbiotic nitrogen fixation”, Hakoyama, T.; Niimi, K.; Watanabe, H.; Tabata, R.; Matsubara, J.; Sato, S.; Nakamura, Y.; Tabata, S.; Li, J.; Matsumoto, T.; Tatsumi, K.; Nomura, M.; Tajima, S.; Ishizaka, M; Yano, K.; Imaizumi-Anraku, H.; Kawaguchi, M.; Kouchi, H.; Suganuma, N. Nature, 2009, 462, 514-517.

3.      “Evidence for a Rapid Degenerate Hetero-Cope-type Rearrangement in Cp*W(S)2-CH2-CH2-CH=CH2”, Eweiner, F.; Senda, S.; Bergander, K.; Mück-Lichtenfeld, C.; Grimme, S.; Fröhlich, R.; Aoyama, M.; Kawaguchi, H.; Ohki, Y.; Matsumoto, T.; Kehr, G.; Tatsumi, K.; Erker, G. Chem. Asian J. 2009, 4, 1830-1833.

4.      “Dinuclear Nickel Complexes Modeling the Structure and Function of the Acetyl CoA Synthase Active-Site”, Ito, M.; Kotera, M.; Matsumoto, T.; Tatsumi, K. Proc. Nat. Acad. Sci. USA. 2009, 106, 11862-11866.

5.      “Organometallic Chemistry in [NiFe] Hydrogenases: Synthesis of the Structural and Functional Models”, Matsumoto, T.; Ohki, Y.; Tatsumi, K. J. Syn.Org. Chem. Jpn. 2009, 540-553 (特集号錯体化学と合成化学の接点, invited paper).

6.      “Synthesis and Reactions of Mono- and Dinuclear Nickel(I) Thiolate Complexes”, Ito, M.; Matsumoto, T.; Tatsumi, K. Inorg. Chem. 2009, 48, 2215-2223.

7.      “Cationic and Anionic Dinuclear Nickel Complexes [Ni(N2S2)Ni(dtc)]n (n = –1, +1) Modeling the Active Site of Acetyl-CoA Synthase”, Song, Y.; Ito, M.; Kotera, M.; Matsumoto, T.; Tatsumi, K. Chem. Lett. 2009, 38, 184-185.

8.      “Structural Models for the Active Site of Acetyl-CoA Synthase: Synthesis of Dinuclear Nickel Complexes having Thiolate, Isocyanide, and Thiourea on the Nip Site”, Ito, M.; Kotera, M.; Song, Y.; Matsumoto, T.; Tatsumi, K. Inorg. Chem. 2009, 48, 1250-1256.

9.      “Modulation of Third-Order Nonlinear Optical Properties by Backbone Modification of Polymeric Pillared-Layer Heterometallic Clusters”, Zhang C.; Cao, Y.; Zhang, J.; Meng, S.; Matsumoto, T.; Song, Y.; Ma, J.; Chen, Z.; Tatsumi, K.; Humphrey, M. G. Adv. Mater. 2008, 20, 1870-1875.

10.   “Synthesis of Ge2NiS4 Clusters and the Thermal Transformation to a Ge4Ni6S12 Cluster”, Matsumoto, T.; Matsui, Y., Ito, M.; Tatsumi, K. Inorg. Chem. 2008, 47, 1901-1903.

11.   “A Functional Hydrogenase Model: Reversible Interconversion of H2 and H2O by a Hydroxo/Sulfido-Bridged Dinuclear Ruthenium–Germanium Complex”, Matsumoto, T.; Nakaya, Y.; Itakura, N.; Tatsumi, K. J. Am. Chem. Soc. 2008, 130, 2458-2459.

12.   “Heterolytic Dihydrogen Activation by a Sulfido- and Oxo-Bridged Dinuclear Germanium-Ruthenium Complex”, Matsumoto, T.; Nakaya, Y.; Tatsumi, K. Angew. Chem. Int. Ed., 2008, 47, 1913-1915.

13.   “Synthesis of syn-2,4-Dimercapto-1,3,2,4-dithiadigermetane and Its Application for Ge2PdS4 Cluster Synthesis”, Matsumoto, T.; Matsui, Y.; Ito, M.; Tatsumi, K. Chem. Asian J. 2008, 3, 607-613. (Highlighted in the Cover picture).

14.   "Dinuclear Nickel Complexes Modeling Acetyl-CoA Synthase", Matsumoto, T.; Ito, M.; Tatsumi, K. J. Biol. Inorg. Chem. 2007, 12, S121-122.

15.   “Nickel(II) Thiolate Complexes with a flexible cyclo-{Ni10S20} Framework.”, Zhang, C.; Takada, S.; Kölzer, M.; Matsumoto, T.; Tatsumi, K. Angew. Chem. Int. Ed., 2006, 45, 3768-3772. (Highlighted in the Frontispiece).

16.   “Synthesis of Oxo- and Sulfido-Bridged Germanium-Ruthenium Complexes and Reactions on the Chalcogenido Bridges.”, Matsumoto, T.; Nakaya, Y.; Tatsumi, K. Organometallics, 2006, 25, 4835-4845.

17.   “Mono{Hydrotris(mercaptoimidazolyl)borato} Complexes of Manganese(II), Iron(II), Cobalt(II), and Nickel(II) Halides.”, Senda, S.; Ohki, Y.; Hirayama, T.; Toda, D.; Chen, J.-T.; Matsumoto, T.; Kawaguchi, H.; Tatsumi, K. Inorg. Chem., 2006, 45, 9914-9925.

18.   “A Facile Method for Synthesis of (R)-(–)- and (S)-(+)-Homocitric Acid Lactones and Related a-hydroxy Dicarboxylic Acids from D- or L-Malic Acid.”, Xu, P-.F.; Matsumoto, T.; Ohki, Y.; Tatsumi, K. Tetrahedron Lett., 2005, 46, 3815-3818.

19.   “Symbioimine Exhibiting Inhibitory Effect of Osteoclast Differentiation, from the Symbiotic Marine Dinoflagellate Symbiodinium sp.”, Kita, M; Kondo, M.; Koyama, T.; Yamada, K.; Matsumoto, T.; Lee, K.-H.; Woo, J.-T.; Uemura, D.; J. Am. Chem. Soc., 2004, 126, 4794-4795.

20.   “Chiral Crystallization of a Linear Two-coordinated Palladium(0) Complex Bearing Propeller-shaped Bulky Phosphine Ligands”, Matsumoto, T.; Kasai, T., Tatsumi, K. Chem. Lett., 2002, 346-347.

21.   “Sterically Protected Dipotassium Germanedithiolate” Matsumoto, T.; Tatsumi, K. Chem. Lett. 2001, 964-965.

22.   “1,2,3,4,5,6,7-Hexathiagermepanes: Synthesis, Structures, and the Ring Contraction to 1,2,3,4,5-tetrathiagermolanes”, Matsumoto, T.; Matsui, Y.; Nakaya, Y.; Tatsumi, K. Chem. Lett. 2001, 60-61.